导师风采

刘玉萍

专业代码:1008/1056

专业名称:中药学

学术/专业型:学术型、专业型

职务

  • 副研究员
  • 硕士生导师

—— 个人简介 ——

刘玉萍  博士副研究员硕士生导师,任南京中医药学会中药专业委员会秘书,中国抗癌协会、中华中医药学会会员。

从事中药活性成分/组分的抗肿瘤转移作用机制及新型递药系统的研究。主持课题:国家自然科学青年基金1项,省自然基金青年基金1项,省卫健委面上项目1项,省中管局课题2项,并以项目骨干参与国家级、省级等项目10余项;发表论文63篇,其中以第一作者或通讯作者发表SCI文章8篇;被引用总频次达二百多次;授权及申请专利4项;研究成果获2019年江苏医学科技奖一等奖。

 

在研课题:

[1] 国家自然科学基金(81903858):“基于外泌体诱导cGAS-STING形成炎性肿瘤转移前微环境探讨淫羊藿黄酮的抗肿瘤转移效应与机制”,时间2020.01-2022.12,经费21万,主持。

[2] 江苏省卫生健康委科研项目面上项目(H2019097):“淫羊藿黄酮干预炎性肿瘤转移前微环境介导的肿瘤转移的效应与机制研究”,2020/01-2022/12,经费4万元,主持

[3] 江苏省中医药科技发展计划项目(ZT202111):“兼具重塑转移灶血管和免疫微环境唤醒TILs 功能的中药组分微颗粒用于抗肿瘤转移研究”,2022/01-2024/12,主持


擅长: 从事中药活性成分/组分的抗肿瘤转移作用机制及新型递药系统的研究

—— 发表文章 ——

近三年发表学术论文情况:

[1] Shumei Tu#, Dengxuan Mao#, Mengxin Shi, Huangqin Zhang, Congyan Liu, Xiaoqi Li, Yang Zhao*, Yan Chen*, Yuping Liu*, Icaritin ameliorates extracellular microparticles-induced inflammatory pre-metastatic niche via modulating the cGAS-STING signaling, Phytotherapy Research, 2022, 1-16.

[2] Guo Jian, Zeng Huating, Shi Xinmeng, Han Tao, Liu Yimin, Liu Yuping, Liu Congyan, Qu Ding*, Chen Yan*. A CFH peptide-decorated liposomal oxymatrine inactivates cancer-associated fibroblasts of hepatocellular carcinoma through epithelial-mesenchymal transition reversion. J Nanobiotechnology. 2022, 20(1):114.

[3] Ding Qu*, Yue Qin, Yuping Liu, Tingting Liu, Congyan Liu, Tao Han, Yan Chen*, Chengyao Ma, Xiaoqi Li, Fever-Inducible Lipid Nanocomposite for Boosting Cancer Therapy through Synergistic Engineering of a Tumor Microenvironment. ACS Appl Mater Interfaces. 2020, 12(29):32301-32311. 

[4] Yue Qin, Tingting Liu, Mengfei Guo, Yuping Liu, Congyan Liu, Yan Chen*, Ding Qu*, Mild-heat-inducible sequentially released liposomal complex remodels the tumor microenvironment and reinforces anti-breast-cancer therapy. Biomater Sci. 2020;8(14):3916-3925.

[5] Yuping Liu, Rongping Fu, Shumei Tu, Ding Qu, Congyan Liu, Xiaoqi Li, Yang Zhao, Chengyao Ma, Yan Chen*, Li Tao. Extracellular Microparticles Encapsulated with Diallyl Trisulfide Interfere with the Inflammatory Tumor Microenvironment and Lung Metastasis of Invasive Melanoma. Molecular Pharmaceutics, 2021,18(3):822-835.

[6] Yuping Liu; Haiyan Xing; Xiangliang Jiang; Yan Chen*; Mengmeng Huang; SuyunYu; Network pharmacology-based preventive effect of XZF on cutaneous toxicities induced by EGFR inhibitor, Biomed Pharmacother, 2020, 123:109755.

[7] Yuping Liu, Xiangliang Jiang, Yue Gu, Yan Chen, Preventive effect of Diallyl Trisulfide on cutaneous toxicities induced by EGFR inhibitor, Int Immunopharmacol, 2019, 69:79-87.

[8] Mengfei Guo, Ding Qu, Yue Qin, Yunyan Chen, Yuping Liu, Mengmeng Huang, Yan Chen*. Transferrin-Functionalized Microemulsions Coloaded with Coix Seed Oil and Tripterine Deeply Penetrate To Improve Cervical Cancer Therapy. Mol Pharm. 2019 Dec 2;16(12):4826-4835.

 


—— 学术兼职 ——

南京中医药学会中药专业委员会秘书